How does IARPA work? What are its successes?
Are we not creating some things because of cultural values the same way the Greeks and Romans did?
Do programs that fall out of scope for present institutions have a large threshold cost? If so what is it?
Where are there other areas where temperature is a limiting component?
Is it possible that there are just different scales that value capture can happen on?
Do patents work better when firms are smaller or more uniform size?
Are there any research search software systems that focus on researchers and lab groups instead of papers?
How did Deepmind Start?
Why didn’t new husbandry techniques occur until 1500?
How do the statements about video games compare and contrast to statements about drugs?
Why was the separation of silver from copper ores so important?
What makes a Florence start being a Florence?
What are the different startup versions that have established sales channels?
How do we get more awesome sci-fi shit?
If we ever encountered alien technology, could we even reverse engineer it?
How does the Zettlekasten system deal with concepts?
How can you tell if an expert has a minimum level of proficiency to wield power or speak to a platform?
How do you systematize going against the system?
Could you actually build a video game to find talent, or would you simply need to use a video game that exists?
What open problems are there in crypto?
Why were rails necessary for railroads (ie. Why didn’t they just invent giant steam powered carriages?)
What do you do when you just see a connection between two pieces of literature?
Where would a 2D picture converted to a 3D model be useful?
How do you operationalize trust?
Is electrical engineering moving fast?
What if there were an API for more resources in the physical world?
Why is working on 5 different things at 20% worse than working on 1 thing at 100%?
Were there other corporations that created R&D labs to avoid anti trust?
Where was the locus of research in the industrial revolution?
How much does hope matter for technological progress?
What does a future with quantum computing look like?
How do you turn open systems into closed systems?
Is it essential that a research org is a small fraction of the money factory’s budget?
Have they tried combining 3D printed engines with generative designs?
Are there proxy questions for how to pitch something to someone?
How often do people realize a Florence while it is still a Florence?
Is it better or worse to have more categories of goals?
How successful did DARPA look ten years in?
Has anybody come up with a way to map institutions?
How do you identify where a technology is on an S-Curve?
In startup studios, how are the incentives set up to stay vs. spin?
What are the principles of a shared zettlekasten?
What is the evidence that anti-monopoly restrictions harmed the economy?
What are the success rates of incubators?
Can you get VC-level returns by funding research?
How do you deal with the tradeoff that technology commoditizes things but high margins are necessary to invest in technology?
Why didn’t the romans create lateen sails?
Is there a valuable dataset in research science and technology
How do you find the note that is on the tip of your mind?
Why aren’t there anonymous podcasts?
Is the gap between best practice and average practice described in lever of riches during the renaissance still the case?
How does patent analysis currently work?
What does it mean to be 100 years behind technologically?
How do you do reference notes for fiction?
What if everything had an expiration date or term limits?
Why weren’t buttons invented in Asia?
Are there ideas that create a lot of value for a big company but would make terrible startups?
Are there more interstellar objects entering the solar system or are we better at detecting them?
Which places are world-class without being a top city?
How does biochar work?
What tools does the video game industry need?
Where could you find a list of inventions that were rejected because there wasn’t a business case?
Does spaced repetition on friends make Dunbar’s number go up?
How do you find counterfactuals?
How can you systematically avoid Parkinson’s Law?
What if you had someone at the top of each research institution whose job is to see what’s cool inside?
What makes a Florence stop being a Florence?
Could you genetically engineer high quality wood to grow quickly?
Why was Bell Labs Different?
Why is “advance technologies that could be critical to national security” quantifiable but “revolutionizing our understanding of the human brain” is not?
Do communities necessarily need not-busy people to curate them?
If you were to use video games as recruiting tool, which of the traditionally valuable skills could you capture and how would you do it?
What ‘humanities’ discipline is the most rigorous? Ie hardest to bs or laze your way through?
How do you send personalized messages at scale?
Are there counterexamples to the idea that it is important for big things to start small?
Where are the lines between the slip box and resources?
Why are quantum leaps important?
Are there more places where instead of spending a lot of effort to get a high quality thing, you could just couple a high variance process with inherent value with strong filtering?
Is it possible that there is a relation between financialization and missing progress? What is it? Which way does causality run?
What if you had a list of all the labs in the world?
How do you make something recession proof?
How do you structure attention so that you connect to the right microexpertise at the right time?
Do we perceive knowledge as an accurate prediction engine?
What gave Israeli VC’s more patience?
How does Mokyr’s Invention and Innovation compare/contrast with Invention and Discovery?
What is a spin-triplet superconductor?
Has anybody studied what made Paris Paris?
Being propelled to a new stratosphere to achieve more things - can it happen to everybody who deserves it?
What are the implications of the definition of invention in Lever of Riches?
What are the passed-over ideas today?
Are there examples of successful “gameification” where there was a successful game that actually obeyed another goal?
Where could you find a list of patents that failed to gather sufficient evidence?
Does the additively manufactured motor get better or worse with size? How?
When is it better to work on things secretly and when in the open?
How do people handle units in databases?
Does the money factory need to necessarily be one organization?
What do learning curves look like for different fields and jobs?
What if your mission was “create technological surprise?”
Are there examples of successful reverse engineering more “advanced” technology in history? Where are the limits?
Why was the breast wheel not invented until the industrial revolution?
Why is it important to have friends you can share slices of life with?
What are the implications of investing being a manufacturing process?
What other organizations are similar to Lux Research?
How do you set up a system where reality is incentivized?
Why do we seem to be in a world where humanity is retreating into a world of digital imagination?
Where else has Wright’s law applied? Where has it not applied when it should have?
Which inventions does the dispensability axiom not hold for?
Is pouring money into adventures similar to pouring money into startups?
Why did funding breakthrough research only focus on DARPA and ARPA-E?
What is a Cooper Pair?
Do clear standards actually lead to more innovation because you have a target?
What makes a Florence Sticky For People?
Why does breaking a Cooper pair kill superconductivity?
Has anybody come up with a good theory of risk aversion focused on innovation?
What is the history of Universities with respect to research?
What would a 50 percent increase in power density enable that hasn’t been?
What is keeping additively manufactured electric motors from getting to 50 percent efficiency?
What was Robert Mushet’s thought process when he figured out how to improve steel?
Has anybody written about how the structure of organizations and their funding are coupled?
Why do companies want R&D off their balance sheets?
Has anyone done something like the polymath project outside of math/cs?
Why don’t we have ground effect vehicles?
Are we actually living in a world where humanity is retreating into a world of digital imagination?
Why hasn’t the challenges slide about ceramic engines been updated since 2015?
If lit notes should be resummarizations, what about the juicy details or examples from references?
Why was Europe slow to adopt paper?
When is externalized research better than internalized research and vice versa?
What are examples of technology being combined well?
How do public-private partnerships start?
When you’re working on something crazy, how do you tell a well meaning person that you don’t want to have to justify it to them right now?
What if instead of doing knowledge maps where you draw connections between papers, you model it with people as the nodes and papers as the edges?
How do you know which concepts in each discipline are most powerful?
Is there something underlying the obsession with talent - ie. Is it the sign of a slack system?
What is the status of Steel-slag based cement systems?
Who will make the best PARPA PMs?
Was Bell Labs an anomaly?
Is it more effective to just present a vision and see if people are bought into it than trying to axiomatically build up the argument?
How does DARPA strike a balance between problem-focus and solution focus?
What is the knowledge that you can get only by physically going to a place?
Why hasn’t Bell Labs been replicated?
What are IARPA Seedlings?
How does the definition of invention in Lever of Riches compare with the definition in Cycles of Invention and discovery?
What do you think will work to enable more quantum leaps?
How many high-alpha resources can there be?
Does more valuable research actually happen on the coasts or are there just better commercialization mechanisms there?
How do you predict where phase transitions occur in materials?
Where does “you need buy-in from the top down” not hold in Big Companies?
Why doesn’t economics use a probabilistic physics model per quantum physics?
What made Florence a Florence?
Why haven’t people started building airplanes with ceramic engines?
How do you have an interview that isn’t just secretly answering the question “do you like this person?”